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Studi scientifici principali



    1. Indicazioni terapeutiche approvate da EMA

    2. Hézode C. et al., Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial, Lancet. 2015 Mar;

    3. Sulkowski MS. Et al.,  Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial.JAMA. 2015 Mar;

    4. Chayama K. et al.,  Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced hepatitis C virus-infected patients. Hepatology. 2015 May;

    5. Poordad F. et al.,  ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis. N Engl J Med. 2014 May

    6. Ferenci P.,  ABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCV. N Engl J Med. 2014 May

    7. Zeuzem S. et al,  Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014 Ap

    8. Feld JJ et al., Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014 Apr

    9. Kwo PY et al.,  An interferon-free antiviral regimen for HCV after liver transplantation N Engl J Med. 2014 Dec

    10. a - TURQUOISE-III Study: ombitasvir/paritaprevir/ritonavir + dasabuvir for genotype 1b with cirrhosis - Feld JJ. J Hepatol 2016; 64:301-7

    11. X – Co-Formulated Ombitasvir and Paritaprevir/ritonavir with ribavirinm in adults with Hepatitis C Virus Genotype 4 infection and Cirrhosis /AGATE-I): a randomised open-label trial

    12. Asselah et al. – Lancet Gastroenterology 2016


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